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KMID : 0043320070300080932
Archives of Pharmacal Research
2007 Volume.30 No. 8 p.932 ~ p.937
Flavonoid Glycosides from Prunus armeniaca and the Antibacterial Activity of a Crude Extract
Rashid Fahima

Ahmed Rehana
Mahmood Azhar
Ahmad Zaheer
Bibi Nazia
Kazmi Shahana Urooj
Abstract
Investigations on the chemical constituents of the fruits of Prunus armeniaca have led to the isolation of two new flavonoid glycosides, 4¡¯,5,7-trihydroxy flavone-7-O-[¥â-D-mannopyranosyl (1¡¯¡¯¡¯¡æ2¡¯¡¯)]-¥â-D-allopyranoside (1) and 3,4¡¯,5,7-tetrahydroxy-3¡¯,5¡¯-di-methoxy flavone 3-O-[¥á-Lrhamnopyranosyl (1¡¯¡¯¡¯¡æ6¡¯¡¯)]-¥â-D-galactopyranoside (2), from the butanolic fraction of the fruits. The butanolic extract exhibited antibacterial activity against both Gram positive and Gram negative bacteria. The structures of these compounds were elucidated through spectral studies, including 2D-NMR (COSY, NOESY, J-resolved), HMQC and HMBC experiments.
KEYWORD
Prunus armeniaca, Fruits, Flavonoid glycosides
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